Definition
A 3D aggregate often used as a simpler 3D model than organoids; commonly in oncology and drug response.
Why it matters
For scientific teams:
- Provides a scalable entry point into 3D biology.
- Improves relevance over 2D culture while remaining simple.
- Useful for high-throughput screening.
For decision-makers:
- Lower complexity than organoids with improved biological relevance.
- Suitable for screening-scale workflows.
- Supports cost-effective 3D assay adoption.
FAQ
Q: How are spheroids formed?
A: Typically via low-adhesion culture conditions or aggregation methods.
Q: When are spheroids preferred over organoids?
A: When simplicity, scalability, or throughput is prioritized.