IonFlux Consummables

IonFlux Plates

Unique in-plate liquid handling, patching and recording

IonFlux uses a unique plate design that allows for all fluid activity to be conducted within the recording plate proper. Using flexible and user controlled pneumatic system, IonFlux provides high speed liquid exchange, continuous solution flow, and drug delivery without the use of an external liquid handler. The in-plate movement of solutions cancels typical ion channel assays problems such as stacking related drug cross contamination. The continuous flow system alleviates assays with slow acting or sticky compounds. IonFlux plate design on the cover of Assay and Drug Development in 2012
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Design

IonFlux Plates are microfluidic devices used exclusively in the IonFlux System for automated patch clamp assays. They are integrated into SBS-standard well plate formats for convenience and compatibility with automated liquid handling instrumentation. Multiple plate formats are available which correspond to the IonFlux system configuration. Each well on the plate has a dedicated function as either a compound well, cell trapping well, cell inlet or cell outlet well.

Plates are divided into experimental patterns. Each pattern contains specified wells:

wellplatediagram
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Format

IonFlux plates come in two standard designs, 96 well plates for use with lonFlux Mercury 16 and 384 well plates for use with lonFlux Mercury HT and ULTRA.
IF Plates Underside
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Recording

IonFlux plates come in two different cell trapping and recording designs:

All IonFlux instruments can use either plate design with no hardware modifications.

Single vs ensemble
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Plate Types

IonFlux plates are shipped in boxes of 8 pieces.

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