Cell Microsystems Lab Services
Contract Research Services
Cell Microsystems offers customized lab services to expedite your research, including:
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Cell Line Development
Utilizing CellRaft® technology, we generate gene edited cell lines, even from challenging or rare cell types, with results in weeks, not months. -
3D Organoid Generation and Screening
Whether it is matrix-based or bioreactor-based 3D cell culture, we can build reproducible assays for drug discovery pipelines using CellRaft and CERO 3D technologies. -
Hematology and Oncology Drug Screening:
We can perform platelet adhesion and cell invasion assays using BioFlux Shear Flow Systems to mimic physiological conditions for drug safety testing. -
Functional Ion Channel Analysis:
With IonFlux Automated Patch Clamp Systems, we can test for drug safety or ion channel dynamics for detailed electrophysiological analysis. Looking to build a custom cell line for electrophysiology? We can do that too.
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Accelerated cell line development
Using our innovative CellRaft technology, we can generate monoclonal cell lines in weeks not months, even from heterogeneous populations containing rare cells of interest. -
Clone challenging cell lines
Many cell lines fail to grow after single-cell sorting or limiting dilution. We have successfully generated monoclonal lines from over 100 different cell types, including stem cells and primary cells. See how we have solved challenges for other labs with the Clone Challenge program. -
Image- and phenotypic-based validation
Using the CellRaft AIR, we can assure monoclonality through imaging, and we can use our suite of analytical tools to confirm the desired edit or phenotype.
Your Samples or Ours...
FAQs
Who are Cell Microsystems’ lab services for?
What type of services are offered?
- We offer lab services for a wide variety of applications, including:
- Cell line development
- 3D model development
- Shear flowFluid movement that applies force to cells and biofilms; used to mimic physiological/pathological conditions. assays, such as cell adhesion assays
- Ion channel patch clamp testing
- These are just a few examples of lab services offered by Cell Microsystems. For a more expansive list, check out the individual instrument services FAQs. Still don’t see the service you’re looking for? Contact a lab services specialist today to chat.
What are the advantages of lab services?
- Less headaches due to assistance with assay development and data analysis: Tell us what your end goal is and we will work with you to design the best experiment possible within your budget. In addition, our expert scientists will provide analysis reports at the completion of the experiment.
- Time-savings: We will run the experiment for you, giving you back your precious time.
- Rapid turnaround: Our scientists are experts, meaning experiments are conducted efficiently, getting you data faster.
When will I get my data?
Contact us to check in on your experiment and our lab services team will gladly update you on the progress and results. We will also send you a full data report after the experiment is completed.
How much do lab services cost?
Lab service costs vary based on experimental requirements, such as the number of assays, replicates, and required scientist(s) time. However, using Cell Microsystems’ lab services means no capital costs, no equipment training, and no operator training are required. Just contact us to request a proposal, and we’ll help you design a study that meets your experimental goals and budget.
How long do lab services take?
The amount of time needed to obtain results is highly dependent on the experiment’s design and requested endpoints. To obtain an estimate of lab services turnaround, please contact our lab services specialist.
Does purchasing or owning a Cell Microsystems instrument (BioFlux, CellRaft AIR, CERO 3D, IonFlux) mean that I can’t use lab services?
Can I purchase a Cell Microsystems instrument after using lab services?
CellRaft AIR
What types of cells have been cloned using the CellRaft AIR?
For a list of cell lines that we have successfully generated monoclonal cell lines from, click here. Don’t see your cell type? Don’t worry! Contact a lab services specialist to discuss your experimental requirements.
Can CellRaft AIR sort my tagged, edited population instead of using FACS?
Yes! Our CellRaft Cytometry softwareCompanion software to the CellRaft AIR instrument enabling image analysis of cells, including verifying single cells and performing phenotypic selection, for mapping CellRafts for automated isolation. can identify cells of interest using label-free brightfield analysis and fluorescence. Together, this allows us to select cells, monoclonal colonies, or organoids based on desired morphology and fluorescent phenotypes, including rare populations.
Can CellRaft AIR isolate single cells or organoids for nucleic acid isolation?
Yes! Lab services can work with you to design custom sequencing or -omics experiments and isolate your desired single cells, clones, or organoids for RNA or DNA extractions.
Do you spend months screening thousands of hybridomas, B-cells, or CHO cells to find antibody producers? Our lab services team is here to help.
Our antibody assay combines the power of single-cell screening for antibody secretion with the scale of over 100 384 well plates, all in just one consumable. We bring the power of CellRaftA microscale polystyrene growth surface within an array used to spatially segregate cells/colonies while maintaining shared media access, enabling imaging over time and targeted isolation. Technology to your antibody discovery workflows—so you can move your projects forward faster.
We can help with:
- clone rescue from unstable or low-producing lines
- functional screening of hybridomas or plasma cells
- development of custom antibody-expressing cell lines
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Increase your predictive power with custom organoid assays
Using CellRaft Technology, we can create custom, single organoid assay plates for downstream testing using organoids derived from adult stem cells, pluripotent stem cells, or patient-derived cancer organoids. -
Reproducible organoid assays
Using the CellRaft AIR, we can image and select single, spatially segregated organoids over time, monitoring growth and/or differentiation, including organoid diameter, shape, and dimensionality, reducing inter- and intra-assay variability. Let us help you design and execute reproducible organoid assays, including drug efficacy and toxicity studies using single organoids. We work with you to design endpoints based on your research goals, from viability and toxicity assays, ELISAs, and qPCR, or we can send cell lysate back to you for assessment in your own lab. -
Create edited, monoclonal organoid lines
The CellRaft Technology is uniquely suited for generating and verifying, via temporal imaging, monoclonal organoid propagation. We have successfully generated monoclonal organoids from a variety of samples. See application note
FAQs
Who are Cell Microsystems’ lab services for?
What type of services are offered?
- We offer lab services for a wide variety of applications, including:
- Cell line development
- 3D model development
- Shear flow assays, such as cell adhesion assays
- Ion channel patch clamp testing
- These are just a few examples of lab services offered by Cell Microsystems. For a more expansive list, check out the individual instrument services FAQs. Still don’t see the service you’re looking for? Contact a lab services specialist today to chat.
What are the advantages of lab services?
- Less headaches due to assistance with assay development and data analysis: Tell us what your end goal is and we will work with you to design the best experiment possible within your budget. In addition, our expert scientists will provide analysis reports at the completion of the experiment.
- Time-savings: We will run the experiment for you, giving you back your precious time.
- Rapid turnaround: Our scientists are experts, meaning experiments are conducted efficiently, getting you data faster.
When will I get my data?
Contact us to check in on your experiment and our lab services team will gladly update you on the progress and results. We will also send you a full data report after the experiment is completed.
How much do lab services cost?
Lab service costs vary based on experimental requirements, such as the number of assays, replicates, and required scientist(s) time. However, using Cell Microsystems’ lab services means no capital costs, no equipment training, and no operator training are required. Just contact us to request a proposal, and we’ll help you design a study that meets your experimental goals and budget.
How long do lab services take?
The amount of time needed to obtain results is highly dependent on the experiment’s design and requested endpoints. To obtain an estimate of lab services turnaround, please contact our lab services specialist.
Does purchasing or owning a Cell Microsystems instrument (BioFlux, CellRaft AIR, CERO 3D, IonFlux) mean that I can’t use lab services?
Can I purchase a Cell Microsystems instrument after using lab services?
-
Improve physiological relevance
Culture, assay, and image cells under shear stress up to 200 dyn/cm2 using our BioFlux shear flow system to improve the physiological relevance of your in vitro studies. -
Reveal in vivo cellular biology
Conducting assays under shear flow can reveal significant changes in gene expression, cytokine production, and cell morphology that may be overlooked in static assays. -
Precisely control shear flow experiments
In addition to delivering precise shear stress, the BioFlux shear flow system offers full control of gas composition and temperature, allowing for a wide range of assays under variable environmental conditions.
Your Samples or Ours...
Studies can be run with samples that you provide (cell lines, primary cells, etc.). Clients can arrange for their own samples to be sent to our labs for the experiments, or Cell Microsystems can acquire samples to your specifications from our network of sample sources.
FAQs
Who are Cell Microsystems’ lab services for?
What type of services are offered?
- We offer lab services for a wide variety of applications, including:
- Cell line development
- 3D model development
- Shear flow assays, such as cell adhesion assays
- Ion channel patch clamp testing
- These are just a few examples of lab services offered by Cell Microsystems. For a more expansive list, check out the individual instrument services FAQs. Still don’t see the service you’re looking for? Contact a lab services specialist today to chat.
What are the advantages of lab services?
- Less headaches due to assistance with assay development and data analysis: Tell us what your end goal is and we will work with you to design the best experiment possible within your budget. In addition, our expert scientists will provide analysis reports at the completion of the experiment.
- Time-savings: We will run the experiment for you, giving you back your precious time.
- Rapid turnaround: Our scientists are experts, meaning experiments are conducted efficiently, getting you data faster.
When will I get my data?
Contact us to check in on your experiment and our lab services team will gladly update you on the progress and results. We will also send you a full data report after the experiment is completed.
How much do lab services cost?
Lab service costs vary based on experimental requirements, such as the number of assays, replicates, and required scientist(s) time. However, using Cell Microsystems’ lab services means no capital costs, no equipment training, and no operator training are required. Just contact us to request a proposal, and we’ll help you design a study that meets your experimental goals and budget.
How long do lab services take?
The amount of time needed to obtain results is highly dependent on the experiment’s design and requested endpoints. To obtain an estimate of lab services turnaround, please contact our lab services specialist.
Does purchasing or owning a Cell Microsystems instrument (BioFlux, CellRaft AIR, CERO 3D, IonFlux) mean that I can’t use lab services?
Can I purchase a Cell Microsystems instrument after using lab services?
BioFlux
Who are BioFlux lab services for?
BioFlux lab services are for anyone who would like to improve the physiological relevance of their investigations by culturing cells under shear flow conditions. We accept service requests from all scientists in both academia and industry.
What type of cells can be used in BioFlux lab service experiments?
Studies can be conducted using samples that the customer provides, including whole blood, isolated primary cells, cancer cell lines, and more. Customers can arrange for their samples to be sent to our lab or Cell Microsystems can use our network of sample sources to acquire samples to match your specifications. If you have concerns about whether your sample will work, please reach out to our lab services specialist (https://cellmicrosystems.com/contact-us).
What assays can BioFlux lab services conduct?
Leveraging the BioFlux shear flow systemA shear-flow platform compatible with inverted microscopes designed for running multiple parallel experiments in microfluidic plates with controlled flow. along with Montage Plus analysis software, previous successful assays include:
- Adhesion strength
- Atherosclerosis models
- Cancer cell homing
- Cancer migration & invasion
- CAR T cell function
- Chemotaxis
- Leukocyte adhesion cascadeA multistep process that facilitates the recruitment and migration of white blood cells to sites of inflammation or infection; observed in several steps, rolling adhesion, firm adhesion, transmigration.
- Metastasis
- Platelet aggregation & adhesion
- Stem cell differentiation
- Transmigration
- Tumor microenvironment
- Wound healing
If you have an assay in mind that is not on the list, please reach out to our lab services specialist to discuss your experiment.
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Accelerate drug discovery and development
High-throughput, streamlined, automated whole-cell patch clamp recordings can greatly reduce testing timelines. -
Explore true ion channel kinetics
Precise delivery and removal of ion channel targeted compounds ensure low-background, high-quality data. -
Investigate mechanisms
Voltage clamp recordings enable deep discovery of how individual ion channels contribute to pathologies and drug candidate function.
mCells
For consistent and quick results, you can select from our validated mCells. All channels are expressed in HEK-293 cells.
Available Ion Channels:
- GABA A α1β2γ2L
- GABA A α2β2γ2L
- GABA A α3β2γ2L
Your Samples or Ours...
FAQs
Who are Cell Microsystems’ lab services for?
What type of services are offered?
- We offer lab services for a wide variety of applications, including:
- Cell line development
- 3D model development
- Shear flow assays, such as cell adhesion assays
- Ion channel patch clamp testing
- These are just a few examples of lab services offered by Cell Microsystems. For a more expansive list, check out the individual instrument services FAQs. Still don’t see the service you’re looking for? Contact a lab services specialist today to chat.
What are the advantages of lab services?
- Less headaches due to assistance with assay development and data analysis: Tell us what your end goal is and we will work with you to design the best experiment possible within your budget. In addition, our expert scientists will provide analysis reports at the completion of the experiment.
- Time-savings: We will run the experiment for you, giving you back your precious time.
- Rapid turnaround: Our scientists are experts, meaning experiments are conducted efficiently, getting you data faster.
When will I get my data?
Contact us to check in on your experiment and our lab services team will gladly update you on the progress and results. We will also send you a full data report after the experiment is completed.
How much do lab services cost?
Lab service costs vary based on experimental requirements, such as the number of assays, replicates, and required scientist(s) time. However, using Cell Microsystems’ lab services means no capital costs, no equipment training, and no operator training are required. Just contact us to request a proposal, and we’ll help you design a study that meets your experimental goals and budget.
How long do lab services take?
The amount of time needed to obtain results is highly dependent on the experiment’s design and requested endpoints. To obtain an estimate of lab services turnaround, please contact our lab services specialist.
Does purchasing or owning a Cell Microsystems instrument (BioFlux, CellRaft AIR, CERO 3D, IonFlux) mean that I can’t use lab services?
Can I purchase a Cell Microsystems instrument after using lab services?
IonFlux Mercury
Can a heterogeneous cell population be tested?
Can IonFlux collect the same data as a manual patch clamp system?
What types of ion channels can you test?
Do you work with transient transfection?
Yes, although the acceptability of the assay is determined on a case-by-case basis.