No More Limiting Dilution
Tired of Being Limited by Limiting Dilution?
Traditionally, a limiting dilution method is used to isolate and generate single cell-derived clones, however, it is both time and cost prohibitive due to low efficiency of success and the manual labor input required.
CellRaft® Technology offers an affordable, automated solution to an otherwise labor-intensive workflow while:
- maintaining cell health
- providing time-course imaging for clonal verification
- delivering automated isolation of cells, colonies, or organoids
Accelerate Cell Line Development by Isolating Colonies, Not Single Cells
Compare Technologies
- What is the quickest way to get single cell colonies?
- How can I increase the viability of monoclonal colonies?
- How can I get image-based proof of monoclonality?
Grow More Colonies
Single cells are grown in a flask-like environment, without physically separating them, eliminating perturbation to cell physiology and ensuring the viability and vitality of single cells as they develop into clones. The CellRaft AIR® system is able to scan more than 40,000 individual cells per CellRaft Array, which is 500X more cells than a traditional 96-well plate with limiting dilution.
Limiting Dilution vs. CellRaft Technology
Confluent colonies
(>50% confluent 10 days post-seeding)
Save Time and Money – Reduce the Cost per Clone
Experimental and cost analyses including hands-on time to run the protocol between limiting dilution and CellRaft Technology indicate that the latter delivers a high return on investment in terms of outgrowth efficiency, time, and cost.
Compare Limiting Dilution to CellRaft Technology
Finally! Image-based Proof of Monoclonality
Time-course imaging is a key feature of the CellRaft AIR System. After cells are seeded on the CellRaft Array, the array is serially scanned at the desired frequency to capture complete growth records of clonal development.
Convince Your Lab to Try CellRaft Technology
- Download and circulate the petition
- Download and customize prewritten letter
- Download the RaftNote comparing limiting dilution to CellRaft Technology
- Submit the request to PI or Lab Manager
