Oncology Research Applications

Engineered T cells, CTCs, and Tumor Microenvironment

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Understanding the molecular and cellular mechanisms of cancer progression, and the effect of treatments on these processes, is the key to development of successful treatments.

BioFlux provides a precisely controlled in vitro model for studying the in vivo biology of cancer.

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CAR-T/TCR Engineered T Cell

Accelerate your engineered T cell drug discovery with functional testing of adhesion and transmigration in vitro
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Tumor Microenvironment

Control and manipulate the tumor microenvironment and test potential treatments
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Metastasis

Examine metastasized cancer cells on endothelial monolayers and protein coatings
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Cancer Cell Homing

Create 2 connected micro-environments to study cancer cell homing
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Epithelial-Mesenchymal Transition

Analyze steps of cancer progression and EMT with cancer cells under shear flow
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Cancer Cell Migration & Invasion

Create two adjacent micro-environments to analyze cell migration and invasion.
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Circulating Tumor Cells

Analyze CTC adhesion and clustering under shear flow
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Leukemia

Examine leukocyte adhesion under shear flow conditions
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Cancer Stem Cells

Analyze stem cell homing, adhesion, transmigration, and differentiation under flow.