Cell line development is a key tool and requirement in almost every experimental workflow in drug discovery and development. The ability to track and trace single cells through clonal development is a critical need, not only for research scientists but also for audit trails and regulatory filings. Several tools exist for this process, from simple limiting dilution to the most complex multi-million-dollar automated robotic platforms. Despite the advances in single cell isolation technologies and the emergence of several platforms, a common challenge among users is the lack of efficiency and the impact on cell viability in these workflows.

Managing the inefficiency and the loss of viability is a continued struggle that has come up time and time again in our conversations with researchers about their everyday experimental process. Whether end users chose to solve these issues by working through a high volume of generating single cells or via unnecessarily high investment in multiple systems throughout their workflow, there always seems to be a need for another step or tool in an attempt to improve the process. Without a doubt, the cell line development community has an acute unmet need for one integrated platform that can provide a high number of monoclonal clones in a short amount of time starting from a cell suspension to a healthy single cell-derived colony, while also delivering true direct proof of clonality and a full archive of images for track and trace of events.

The CellRaft AIR® system provides such a platform based on a single CellRaft® Array that allows users to keep cells in a flask-like environment while segregating them for automated isolation from image confirmation of their development into targets of interest. Now there is a tool that allows researchers to attain an average of 75%+ of clonal outgrowth efficiency with 5x fewer consumables and media while providing images for track and trace capability (without spending a million dollars on hardware, software, and reagents). Learn how to eliminate the roadblock of clonal development and see how your research can change! With over 80 cell lines tested, the Cell Raft AIR is uniquely positioned to help in 2D and 3D biology.

Download the white paper that compares technologies and discusses overcoming challenges to learn more. (https://info.cellmicrosystems.com/white-paper-for-monoclonal-cell-lines)

Scott McGinnis, Vice President of Sales

Scott has 25 years of experience talking with researchers about their pain points while working in sales across leading companies in the life science industry, including Life Technologies, Thermo Fisher Scientific, Essen BioScience, and Sartorius, and has developed deep expertise in building and leading teams selling instruments in the microscopy, flow cytometry, and bio-analytical fields. Mr. McGinnis earned a B.A. in Chemistry from the College of Holy Cross.