Overview
Traditional organoidA 3D, self-organizing cell structure, derived from pluripotent or adult stem cells that mimic aspects of organ function and architecture. culture presents challenges in downstream analysis of single organoids. In this webinar, Dr. Allysa Stern reviewed a unique workflow that enables clonal organoidAn organoid derived from a single cell. development, monitoring of iPSC differentiation over time, and automated isolation of single organoids.
Dr. Scott Magness presented a case study related to his group’s work investigating tumor cell heterogeneity through clonal organoid morphology and transcriptomics. He discussed new approaches using single organoid transcriptomics to evaluate organoids derived from single cells from gastric dysplastic tissues and how this approach might reveal new ways to investigate tumor cell heterogeneity and evasion of some cells from cancer treatments.
In this Webinar
- Learn how to accelerate the utility and reproducibility of iPSC-derived organoids
- Learn about clonal tumor organoid transcriptomics
- Gain an understanding of tumor cell heterogeneity
At the conclusion of this webinar, there is an engaging Q&A forum.