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Protecting Innovations

Cell Microsystems actively pursues patent protection for its innovative products and methods of using them

The following products are protected by patents in the U.S. and elsewhere. This page is intended to provide notice under 35 U. S. C. §287 (a) and other jurisdictions that permit virtual patent marking.

Product Name
CellRaft® AIR™ System
U.S. Patent Nos. 9,068,155; 9,765,291; 9,963,666; 9,994,805; and other U.S. and foreign patents pending
CytoSort™ Array 100S, 200S, 100Q, 200Q
U.S. Patent Nos. 9,068,155; 9,963,666; 9,994,805; 10,364,411; and other U.S. and foreign patents pending
CytoSort™ HexaQuad™ Array
U.S. Patent Nos. 9,068,155; 9,963,666; 9,994,805; 10,364,411; and other U.S. and foreign patents pending
CellRaft System for Inverted Microscopes
U.S. Patent Nos. 9,068,155; 9,765,291

Cell Microsystems has both licensed intellectual property from the University of North Carolina at Chapel Hill and has developed multiple inventions internally relating to improving the manufacturability of the product as well as automating its use.

An array of magnetic or paramagnetic micro-elements comprised of polysilsesquioxane is described having ultra-low­autofluorescence and other optical properties to improve microscopic imaging of cells or other object present on the array. These materials are also amenable to chemical modification allowing surface attachment of affinity capture moieties or chemical reporters for selective binding or analysis of cells, macromolecules or other targets.

Describes an automated method and system to isolate and collect cells using computerized image analysis of images of cells and their surroundings obtained from a digital imaging device or system. The system makes use of a “microwell array,” which can comprise a formed, elastomeric grid of indentations or “wells.” Many, most, or all of the wells in a microwell array can contain a releasable, microfabricated element, which can be referred to as a “raft.” A system and method is provided for cell collection that includes computerized identification and collection of rafts with isolated single cells or a specific group or groups of cells, eliminating the need for continuous human identification and selection.

Describes an apparatus for collecting or culturing cells or cell colonies comprising a microwell array formed from an elastomeric material and having a plurality of rigid cell carriers releasably connected within each well, along with methods of use and a device for releasing the cell carriers.

Describes a process of preventing bubble formation in structured surfaces using either hydrophilic or hydrophobic sacrificial layers, depending on the application. Also includes microfabricated devices that can be wetted without bubble formation.