Shear Flow
Stem Cells
Visualization of stem cell interactions under flow helps elucidate stem cell recruitment, differentiation, migration. Stem cells are increasingly studied as potential sources of therapeutic treatment, and the study of these processes under physiological conditions is critical.
The BioFlux system is particularly use for for stem cell studies under physiologically-relevant shear flowFluid movement that applies force to cells and biofilms; used to mimic physiological/pathological conditions. conditions. With this system, recruitment, cell adhesion, and transmigration can be quantitated under continuous flow, providing major work flow advantages over traditional flow cell assays.
Below is an example of a stem cell study using BioFlux
Key BioFlux Advantages For STEM Cell research
- Accurately model the in vivo environment: study stem cell interaction and transmigration to cell layers such as HUVECs
- Generate superior data: utilize time-lapse microscopy under flow and post-experiment image analysis to determine degree of adhesion and transmigration
- Get results fast: examine dozens of different treatments to see the effect on stem cell recruitment
- Easily analyze data: calculate cell numbers adhered/transmigrated by utilizing BioFlux software analysis capabilities
