Pre-Recorded Webinar
Abstract:
It is well known that the GABA(A) receptor is the primary target for the therapeutic actions of benzodiazepines and for many general anesthetics. Both groups of compounds act as GABA(A) receptor positive allosteric modulators (GABAPAMs), increasing the strength of phasic and tonic inhibition in the brain. This seminar will explore our use of conventional and microfluidic electrophysiology in translational research projects that have led us to the discovery of novel endogenous GABAPAMs and new disease mechanisms.
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