The BioFlux system is a microfluidic device and control instrument that is ideally suited for platelet adhesion and aggregation studies. In contrast to parallel plate flow chambers, the BioFlux system does not need to be modified to accommodate pathological shearElevated or altered shear associated with disease states (often used in thrombosis/vascular injury modeling).shear stressThe tangential force per unit area from flowing fluid; a key parameter in vascular biology, platelet function, leukocyte rolling, and biofilm adhesion studies., has much smaller sample requirements, and has higher throughput capabilities. This application note describes platelet function assays performed using the BioFlux system.
Key highlights of this application note include:
1) Adherence to multiple substrates in the same experiment
2) High-throughput pharmacological screening
3) Easily replicate in vivo platelet/vascular interactions
