Antimicrobial screening (biofilms)
Definition
Testing compounds against microbes/biofilms, ideally with real-time imaging and quantitative readouts under relevant flow.
Why it matters
For scientific teams:
- Biofilm responses differ from planktonic cells.
- Enables realistic assessment of antimicrobial efficacy.
- Supports time-dependent kill studies.
For decision-makers:
- Improves predictive value of screening data.
- Supports development of anti-biofilm therapies.
- Differentiates screening platforms.
FAQ
Q: Why screen biofilms separately?
A: They respond differently due to matrix and physiology.
Q: What readouts are common?
A: Biomass, viability, detachment, and kinetics.