Brochures

Looking for more information about our CellRaft AIR® System or CellRaft® Arrays?

Download the following brochures.

CellRaft AIR® System

The CellRaft AIR System  enables workflows to image, identify, and isolate viable single cells or clonal colonies.

Download our CellRaft AIR System brochure to learn more.

CRISPR & Cell Line Development

The CellRaft AIR System is a fully automated and hands-free imaging and isolation solution for limiting manual screening and cell manipulation efforts. 

Download our CRISPR & Cell Line Development application brochure to learn more.

Genomics

Eliminate doublets and debris by automated selection of the best single cells that maintain their native phenotype for downstream genomic analysis. 

Download the Genomics application brochure to get more information.

Stem Cells

The CellRaft AIR System’s Stem Cell Workflow can eliminate expensive additives and provide greater yields to accelerate the path to drug discovery and new therapies. 

Download our Stem Cell application brochure to learn more.

CORE Labs

Accelerate your research by collapsing labor-intensive workflows onto the automated CellRaft AIR system.

Download the CellRaft AIR System for CORE Labs brochure to get more information.

CROs

Tracking and traceability is critical for CROs. Using brightfield microscopy, the CellRaft AIR System identifies single cells and serially images over time to capture complete growth records of clonal development. 

Download our CellRaft AIR System brochure to learn more. 

RaftNotes

RaftNotes are publications specifically for AIR System users that features application updates and product notes.

Image, Identify, and Isolate Single Organoids using the CellRaft AIR® System

The advancement of 3D culture systems has transformed cell-based assays for biological research and drug discovery due to their ability to re-capitulate the structure and cellular complexity of in vivo tissues. Organoids are unique due in their ability to self-organize and closely replicate in vivo pathophysiology. Most laboratory instruments employed to assess endpoints using traditional organoid cultures have limitations that preclude assessment of the heterogeneity within the population or retrieval of single, intact 3D structures for downstream applications.

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Using the CellRaft AIR® System to Image, Identify, and Isolate Suspension Cells

The AIR System offers unique advantages over technologies, such as flow cytometry and droplet dispensers, designed to assess cells in suspension. The limitations to other technologies include impacts on cell viability, inability to interrogate small numbers of cells, and reliance on fluorescent markers or staining for cell characterization. To demonstrate the value of the CellRaft technology for use in suspension cell line development, we have established methodologies for attaching suspension cells to the CellRaft Arrays during single cell expansion while still allowing the cells to expand in suspension after the clone of interest has been isolated.

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Cell Line Development – Comparing Limiting Dilution to the CellRaft AIR® System

Therapeutic proteins play an essential role in the biological pharmaceutical market and are used in the treatment of many diseases, such as diabetes, cancer, and anemia. One of the main goals in recombinant protein development is the establishment of high-quality monoclonal cell lines that consistently express large amounts of the given protein. Chinese hamster ovary (CHO) cell lines have dominated the industry as commercial hosts for recombinant protein production; however, the process of generating a homogenous CHO cell line is not trivial.

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