Accelerate Cell Line Development by Isolating Monoclonal Colonies, Not Single Cells

Key Questions: How can I reduce the time to create a cell bank ? What is the quickest way to get single cell colonies? What is the best way to isolate colonies? How can I increase the viability of monoclonal colonies? How can I do get image-based proof of monoclonality?Authors: Megan Harrison, Cole Peeler, Allysa […]
Antibody Discovery, Screening, and Production using CellRaft® Technology

The development and production of novel monoclonal antibodies (mAbs) requires a method to screen and isolate monoclonal antibody-producing cells. This is often achieved by performing Enzyme-Linked Immunosorbent Assays (ELISAs) on thousands of single cells, a highly laborious and resource-intensive process. Download Poster »
From Static to Shear Flow: Fast, Scalable, and Physiological Leukocyte Adhesion Assays
Download this poster to learn how to conduct physiologically relevant cell adhesion assays in high-throughput.
Establishment and validation of the 3D cultivation system “CERO” for hepatic spheroids to study viral hepatitis
Download this poster to learn how a CERO Cell Culture and Bioreactor System was used to generate healthy spheroids from hepatic cells and keep them viable in long-term culture. Download Poster>>>
High Efficiency Cell Line Development of a Density-Dependent Hepatic Cell Line

If you work with difficult-to-clone cell types, you will appreciate the challenge researchers at this lab faced in generating monoclonal populations of Hep3B human hepatoma cells. To address this issue, these researchers turned to the Cell Microsystems’ Clone Challenge to leverage our CellRaft Technology. In this case study, see how our technology was used to successfully […]
From Manual to Automated: Revolutionizing HiPSC Differentiation by Increasing Efficiency and Fidelity for NPCS, HSPCS, AND LPCS, with CellRaft Technology

Tired of the inconsistency and inefficiency of hiPSC differentiation techniques? We hypothesized that CellRaft Technology could overcome these challenges in differentiating hiPSCs into cell types representing each lineage. Was our hypothesis correct? Download our poster to see. Download Poster Here
Growing Challenging Clones — Case Studies

In this poster, we spotlight the journeys of the six recipients of our 2023 Clone Challenge Grant Giveaway, highlighting the clone challenges they faced and how our team of scientists helped them overcome these obstacles. Each selected applicant sent us their sensitive cells, allowing our team to seed, culture, and image them over time to […]
Sf9 Single-Cell Cloning for Recombinant Protein Production Is Possible with CellRaft Technology

The baculovirus expression vector system (BEVS) is a versatile method for producing recombinant proteins in insects. However, single cell cloning, ideal for stable production cell lines, is challenging with Sf9 cells, causing bottlenecks in BEVS workflows. These cells are sensitive to stressors like low seeding density and high sorting, leading to a reliance on polyclonal […]