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Publication: Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium

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Leukocyte (WBC) interaction and adhesion to platelets and vascular endothelium plays an integral role in the initiation of inflammation. In this investigation, researchers used a BioFlux shear flow system to visualize and quantify leukocyte-platelet interactions in whole blood. The group used a BioFlux to determine that rhVim reduces neutrophil adhesion to endothelial cells and platelets.

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Distinct and convergent effects of SF3B1 mutations in human breast cancer

In this study, CellRaft AIR was used to isolate, verify, and expand monoclonal cell lines carrying engineered SF3B1 mutations, forming the basis of an isogenic...

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A benchmark of the somatic mutation landscape using single-cell and single-molecule whole-genome sequencing

In this work, CellRaft arrays were used to generate clonally derived cell populations from single cells prior to sequencing, providing a ground-truth reference for benchmarking...

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Loss of cell cycle gatekeeping by CNOT3 impairs hematopoietic stem and progenitor cell division and repopulating activity

In this study, CellRaft AIR was used to isolate and track single hematopoietic stem and progenitor cell (HSPC) clones over time, enabling researchers to directly...

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