Recently, some members of the Cell Microsystems team traveled to the United Kingdom, to speak with researchers at some of the institutions associated with the National Biofilms Innovation Center (NBIC). While there, our team was fortunate to speak with several microbiologists who were conducting investigations in two major areas: biofilm drug resistance and antibiofilm drug […]
hERG, patch clamp, cardiac safety, drug discovery, cardiac risk assessment
Fastest growth. Biggest colonies. Healthiest clones. Prettiest morphology. Relying on these commonly used, albeit biased, superlatives to make decisions about which cells are seemingly the “best” can ignore true biological phenotypes. As the story below highlights, the best clone may ultimately be the one that breaks the mold of these canonical criteria. During a recent […]
In a recent webinar, Dr. Jessica Hartman shared her expertise in CRISPR and gene-editing workflows, offering valuable insights into the challenges and solutions for creating reliable, edited cell lines. Here’s a look at the main takeaways and how innovative technology is changing the game for scientists in this field. Addressing the Inefficiencies in Gene Editing […]
The study of biofilm communities presents unique challenges in experimental design and analysis. While mixed bacterial populations offer fascinating insights into microbial interactions and community dynamics, accurately characterizing and investigating these complex systems has previously required sophisticated and tedious technical approaches. Here, we will discuss advances in technology that have helped to simplify and streamline […]
Imagine working with a rare patient-derived cell samples. In a traditional setup, you might need 1 milliliter of sample (equivalent to about 20 drops) to run an experiment. With a microfluidic system, you could potentially get the same results with just 10 microliters (about one-half of a single drop). This efficiency opens up entirely new […]
In the ongoing battle against antibiotic-resistant bacteria, or “superbugs,” scientists are constantly seeking innovative tools to understand the mechanisms of resistance and develop effective treatments. One such groundbreaking technology is shear flow systems, which have emerged as game-changers in microbiological research. By simulating the dynamic conditions of bacteria’s natural environments, such as the human body […]
Cell culture is the backbone of modern biomedical research, drug development, and regenerative medicine. Traditionally, cells are grown in static environments—like petri dishes or flasks—where stationary media can lead to inconsistent results. Today, researchers are adopting shear flow systems that use dynamic media circulation to mimic the natural forces and nutrient dynamics cells experience in vivo. Here’s […]
