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Publication: Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium

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Leukocyte (WBC) interaction and adhesion to platelets and vascular endothelium plays an integral role in the initiation of inflammation. In this investigation, researchers used a BioFlux shear flow system to visualize and quantify leukocyte-platelet interactions in whole blood. The group used a BioFlux to determine that rhVim reduces neutrophil adhesion to endothelial cells and platelets.

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Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance

Researchers at Columbia University used the CellRaft AIR System to support the development of precisely engineered human embryonic stem cell (hESC) lines for a study...

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Distinct and convergent effects of SF3B1 mutations in human breast cancer

In this study, CellRaft AIR was used to isolate, verify, and expand monoclonal cell lines carrying engineered SF3B1 mutations, forming the basis of an isogenic...

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A benchmark of the somatic mutation landscape using single-cell and single-molecule whole-genome sequencing

In this work, CellRaft arrays were used to generate clonally derived cell populations from single cells prior to sequencing, providing a ground-truth reference for benchmarking...

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