Eliminate the pressure of cell sorting
CellRaft® Technology helps scientists overcome the limitations of current technologies for cell sorting, single cell cloning, growing organoids, and isolation, providing significant cost-savings, increased viability, and high outgrowth.
Culture more cells. Save time and money.
Customer Labs Who Have Cited CellRaft Technology
CellRaft AIR® System
Empowering the generation and automated isolation of monoclonal colonies from single cells.
- Grow single cells without physically isolating cells, thus no perturbation to ensure the viability of single cells as they develop into clones.
- Obtain 10 to 50X more viable monoclonal colonies with a high proliferative index (vitality).
- Image, track, analyze, and automate isolation of colonies from single cells on one instrument with no minimum sample size requirement.
- Identify the cells you want the instrument to automatically isolate based on various precise user-based attributes as a function of gene expression-morphology and time.
- Grow colonies from primary, adherent, or suspension cells, including iPSCs and immune cells.
- Grow iPSCs into 3D cell systems, including organoids.
- Maintain a complete record of all clones to accelerate regulatory submissions.
What Customers Say About CellRaft Technology
"We can now easily identify thousands of single organoids with various morphologies (size, shape, complexity) and isolate hundreds in less than an hour. We also use the CellRaft AIR System for cloning of transgenic or CRISPR-edited human intestinal stem cells. Prior to the air system, the efficiency of isolating clonal lines was very inefficient because of the low throughput. Now we can isolate hundreds or thousands of clonal organoids in an unprecedented short amount of time compared to before."
Scott Magness, Ph.D.
Associate Professor, University of North Carolina – Chapel Hill, NC State University Joint Departments of Biomedical Engineering, UNC Departments of Medicine, Cell Biology, & Physiology
"Several adherent lines tested in the lab do not survive sorting at high pressure and their outgrowth is poor when sorted singly in plates. Manually limiting dilution was previously the only process for obtaining clones; however, we can now utilize the CellRaft AIR® system for adherent lines as well."
"We recommend the CellRaft Technology for our colleagues struggling with single cell isolation. Even with help from FACS, although single cell clones could be obtained, from our experiences, CellRaft not only speeds up this process by providing many more clones but more importantly, the unique monitoring process provided by CellRaft supplies additional information for every single clone with a higher quality of clones ."
Pengda Liu
Associate Professor of Biochemistry and Biophysics / Lineberger Comprehensive Cancer Center / The University of North Carolina at Chapel Hill
CellRaft® Arrays
Viable cells, unperturbed phenotypes, better clonal propagation.
- Plate your cells, image your cells, choose your best cells, and isolate them all on one consumable. Drive down the cost per result with more efficient workflows and better downstream results.
- The CellRaft Technology used in our CellRaft Arrays gently sorts your cells, increasing viability and resulting in less perturbed phenotypes, compared to traditional methods.
- Available in six different formats to optimize specific application workflows and outcomes.
Confluent Colonies
(>50% confluent 10 days post-seeding)
CellRaft Technology
No more limiting dilution. Grow more colonies. Save time and money.
CellRaft Technology offers an affordable, automated solution to an
otherwise labor-intensive workflow while maintaining cell health, providing time-course imaging for clonal verification, and delivering automated
isolation of cells, colonies or organoids.
Development of Monoclonal Cell Lines - Available Technologies and Overcoming Challenges
Have you ever wondered what impacts the viability and survival rate of your clones after a single cell cloning protocol? This white paper provides an
overview of current methods for creating monoclonal lines from single cells and discusses the challenges and tips on how to overcome them.
