Applications

Everyday, scientific and medical researchers use the CellRaft AIR system to better understand biology at the single cell level and accelerate advances in discovery

CRISPR

Automating the CRISPR workflow allows for improvement in cell viability, clonality and efficiency so dozens of cell lines can be generated in parallel. Learn more about how our CellRaft AIR System and CytoSort arrays contribute to a reduction in the entire workflow to less than one week for dozens of cell lines, compared to months for just one.

Stem Cells

Working with stem cells presents unique and frequent challenges – particularly with induced pluripotent stem cells and human embryonic stem cells. Generating cell lines, directing differentiation, and reprogramming are all areas that require a gentle approach to capture single cells and culture them under prescribed conditions. The CellRaft AIR System provides an approach to gently isolate single iPS cells or hES cells in distinct microwells on a CytoSort Array.

Genomics

The CellRaft AIR System integrates single cell imaging and viable cell isolation, with no minimum input requirement – and works with virtually any cell type. Learn more about the CellRaft AIR system and how it can accelerate your single cell analysis research.

Organoids

Working with stem cells presents unique and frequent challenges – particularly with induced pluripotent stem cells and human embryonic stem cells. Generating cell lines, directing differentiation, and reprogramming are all areas that require a gentle approach to capture single cells and culture them under prescribed conditions. The CellRaft AIR System provides an approach to gently isolate single iPSCs or hESCs in distinct microwells on a CytoSort Array.

 

LEARN MORE ABOUT PRODUCT APPLICATIONS IN OUR RAFTNOTES

Cell Line Development using the CellRaft AIR® System

Therapeutic proteins play an essential role in the biological pharmaceutical market and are used in the treatment of many diseases, such as diabetes, cancer, and anemia. One of the main goals in recombinant protein development is the establishment of high-quality monoclonal cell lines that consistently express large amounts of the given protein. Chinese hamster ovary (CHO) cell lines have dominated the industry as commercial hosts for recombinant protein production; however, the process of generating a homogenous CHO cell line is not trivial.

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Automated Cloning for CRISPR Workflows Using the CellRaft AIR® System

Gene editing workflows require transformation of a large number of cells, followed by isolation of individual cells from the larger population to establish clonal colonies. Given the large number of gene edits required for contemporary research and the labor-intensive components of the workflow, there is an unmet need to automate post-transformation cloning.

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